Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly.
Description | mouse monoclonal to alpha Tubulin |
Protein full name | Tubulin alpha-1A chain |
Synonyms | TUBA1A, B-ALPHA-1, LIS3, TUBA3, tubulin alpha 1a,TUBA1B, K-ALPHA-1, tubulin alpha 1b |
Isotype | IgG1 |
Purity | Affinity purification |
Subcellular location | Cytoskeleton |
Predicted MW. | 50 kDa |
Observed MW. | 55 kDa |
UniProt ID |
WB | Human, Mouse, Rat | 1: 3000-1: 6000 | lung |
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 2000 | colon |
ICC/IF | Human, Mouse, Rat | 1: 1000-1: 2000 | HeLa |