AmeriDx® Recombinant Human Anti-Muellerian Hormone (AMH/MIS) Protein (Item No 21231235 )
CATALOG NUMBER: 21231235
PROTEIN NAME: Anti-Mullerian Hormone (AMH), Mullerian-inhibiting factor (MIF), Mullerian-inhibiting substance (MIS).
DESCRIPTION:
The Human AMH is synthesized by the granulosa cells of the preantral and early developing antral follicles, belongs to the transforming growth factor beta superfamily [1]. AMH is a hormone involving sex organs development in wombs, and a ovary biomarker for reproduction diseases such as polycystic syndrome[2]. it's primary physiological function in the ovary is to prevent primordial follicles recruitment and regulate FSH secretion in the early follicular phase [3].
SIZE: 0.1 mg/ 1 mg/ 5 mg
SOURCE: human AMH gene cloned into Mammalian cell lines
SEQUENCES (P03971 A453-R560)
AGATAADGPCALRELSVDLRAERSVLIPETYQANNCQGVCGWPQSDRNPRYGNHVVLLLKMQARGAA LARPPCCVPTAYAGKLLISLSEERISAHHVPNMVATECGCRLESRGPEQKLISEEDLNSAVDHHHHHH
HOST: E coli
MOLECULAR WEIGHT: 14.8 kDa
PURITY: >95% by SDS-PAGE analysis
STORAGE BUFFER: 1x PBS with 0.5% trehalose.
RECONSTITION AND STORAGE: This product is shipped with blue ice, please store at freezer below -20oC. Reconstitute with 1x PBS before use.
APPLICATION NOTES: n/a
REFERENCES
1. Pellatt L, Hanna L, Brincat M, et al. Granulosa cell production of anti-Müllerian hormone is increased in polycystic ovaries. J Clin Endocrinol Metab. 2007; 92(1): 240–245, doi: 10.1210/jc.2006-1582. PMID: 17062765.
2. Ozay AC, Emekcı Ozay O, Gulekli B. Comparison of Anti-müllerian Hormone (AMH) and Hormonal Assays for Phenotypic Classification of Polycystic Ovary Syndrome. Ginekol Pol. 2020;91(11):661-667. doi: 10.5603/GP.a2020.0122. PMID: 33301159.
3. La Marca A, Broekmans FJ, Volpe A, et al. ESHRE Special Interest Group for Reproductive Endocrinology--AMH Round Table. Anti-Mullerian hormone (AMH): what do we still need to know? Hum Reprod. 2009; 24(9): 2264–2275. PMID: 19520713.