Warning Cookies are used on this site to provide the best user experience. If you continue, we assume that you agree to receive cookies from this site. OK

Recombinant Human Interferon alpha-inducible protein 27 from E. coli, 100 ug, cat# 21231298

Images
 
Save 10%
Product Details
Summary
List price: $390.00
$350.00
You save: $40.00 (10%)
21231298
In stock
+

Minimum quantity for "Recombinant Human Interferon alpha-inducible protein 27 from E. coli, 100 ug, cat# 21231298" is 1.

Note
 

Recombinant  Human Interferon alpha-inducible protein 27 from E. coli, 100 ug, cat# 21231298

Product Description
 

Recombinant  Human Interferon alpha-inducible protein 27 from E. coli, 100 ug, cat# 21231298

Human interferon alpha-induced protein 27 is a 122 amino acid protein, has has antiviral activity[1,2], prevent the replication of the virus by recruiting both the hepatitis C virus non-structural protein 5A/NS5A (RNA dependent RND polymase, RdRp) and the ubiquitinating machinery via SKP2, promoting the ubiquitin-mediated proteasomal degradation of NS5A.

IFI27 Protein Product Information

Synonym :

IFI27

Protein Construction:

A DNA sequence coding 121 amino acid length of IFI27 mature protein was cloned into ApreBioTM vector, and expressed in BL21.

Source:

Homo sapiens

Expression Host:

  E. coli.

PCT Protein QC Testing

Purity:

> 90 % as determined by SDS-PAGE

SDS-PAGE:

M, AmeriDx protein marker.

10ug (1), 5ug(2), 2.5ug (3)

and 1 ug (4) of Recombinant
Human IFI27 Antigen.

Stability:

Samples are stable for up to twelve months from date of receipt at -70oC/p>

Molecular Mass:

13 kDa on SDS-PAGE gel

Formulation:

lyophilized from the protein solution in sterile PBS, pH 7.4, with 0.02% sodium azide.


Protein Storage

Storage:

Store it under sterile conditions at -70â„? It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Reconstitution:

A hard copy of COA with reconstitution instructions is sent along with the products. Please refer to it for more detailed information.

Product Documents

COA is available upon request.


1. Xue, B., et al. (2016). "ISG12a Restricts Hepatitis C Virus Infection through the Ubiquitination-Dependent Degradation Pathway." J Virol 90(15): 6832-6845.

2. Chen Y, Jiao B, Yao M, Shi X, Zheng Z, Li S, Chen L. ISG12a inhibits HCV replication and potentiates the anti-HCV activity of IFN-α through activation of the Jak/STAT signaling pathway independent of autophagy and apoptosis. Virus Res. 2017 Jan 2;227:231-239. doi: 10.1016/j.virusres.2016.10.013. Epub 2016 Oct 21. PMID: 27777077.

<<

Product PDFs