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Mesothelin Antigen (Cat# 21231208)
Mesothelin is a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.
Mesothelin Protein Product Information
A DNA sequence encoding the human MSLN was expressed, with a N-terminal polyhistidine tag
| Insect cells|
Mesothelin QC Testing Results
> 95 % as determined by SDS-PAGE
Recombinant Human Mesothelin
Samples are stable for up to twelve months from date of receipt at -70â?/p>
The recombinant MSLN protein comprises of 373 amino acids including his tag, and is approximately 42 kDa in SDS-PAGE under reducing conditions
In sterile PBS, pH 7.4, with 0.02% sodium azide.
Store it under sterile conditions at -70â? It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
A hard copy of COA with reconstitution instructions is sent along with the products. Please refer to it for more detailed information.
COA is available upon request.